【摘要】 目的　比较西拉普利与美托洛尔长期治疗对原发性高血压患者肱动脉功能的影响。方法　脉冲多普勒法。结果　两组原发性高血压患者分别接受西拉普利或美托洛尔治疗 6个月后血压均明显下降 ,但西拉普利组的肱动脉管径、血流速度、血流量和扩张性增加 ,血流阻力减少 ;而美托洛尔治疗组的肱动脉管径、血流速度、血流量和扩张性有所下降或无明显改变。结论　西拉普利可以部分改善高血压患者前臂动脉功能更多还原

【Abstract】 Aim:To compare the effect of cilazapril and metoprolol on the compliance of brachial artery in essential hypertension(EH). Methods:Compliance of brachial artery was determined by Pulsed Doppler techniques. Brachial artery diameter(Dd),flow velocity(Vm),volumic blood flow(Q) and the distensibility(Dis) increased markedly,the resistance(R) used as the indexes of compliance of brachial artery. Results:Sixty seven EH were divided into two groups(A,B) randomly. Group A were treated with Cilazaril,Group B with Metoprolol. After 6 months treatment, BP in all the patients decreased. In Group A,the Dd,Vm,Q and Dis increased markedly,but R of brachial artery decreased obviously.In group B,no obvious changes of branchial artery were found. Conclusion:Cilazapril may improve the compliance of brachial artery partially.更多还原