【摘要】 目的 :探讨应用智能声学定量 (AQi)技术检测慢性肺心病患者右室收缩和舒张功能的临床价值。方法 :用心尖四腔心切面 ,以 AQi为指标对 39例慢性肺心病患者和 2 0例正常人右室功能进行了测定。将慢性肺心病分为心功能代偿期 ( 组 )和心功能失代偿期 ( 组 )。 AQi技术的参数包括 EDA、 ESA、 FAC、 PER、 PRFR。结果 :与对照组相比 ,肺心病 组和 组 EDA和 ESA显著增大 ,FAC和 PER显著降低。 组与 组相比 ,以上参数也有显著差异。 组的 PRFR与对照组比较无显著差异。但 组的 PRFR与对照组比较 ,有显著差异。结论 :慢性肺心病代偿期右室收缩功能就已经受损 ,并且随着病情的进展 ,损害进一步加重。而舒张功能在心功能失代偿期才出现明显损害 ,慢性肺心病右室收缩功能受损早于舒张功能。 AQi技术能够准确、实时地反应右室功能更多还原

【Abstract】 Objective:To dicuss the clinical values of intelligent acoustic quantification(AQi)used to detect right ventricular systolic and diastolic functions in chronic cor pulmonale patients.Methods:Using AQi as a criteria,we assessed the right ventricular functions in 39 chronic cor pulmonale patients and 20 normal subjects in the apical four chamber view.The chronic cor pulmonale patients were subdivided into two groups:the cardiac function compensated group(Ⅰ)and the uncompensated group(Ⅱ).The parameters of AQi technique include end diastolic area(EDA),end systolic area(ESA),Fraction area change(FAC),peak ejection rate(PER)and fast peak filling rate(FPFR)of the right ventricle.Results:EDA,ESA of AQi parameters in chronic cor pulmonale patients were enhanced significantly compared to those of the normal.FAC,PER were decreased significantly.There was significant diference between group Ⅰ and group Ⅱ in those parameters.There was no difference in PRFR between the group 1 and the normal,but there was really evident difference between the group Ⅱ and the normal.Conclusions:The systolic function during the compensated period in chronic cor pulmonale patients has already been injured and this kind of injury will be further aggravated with the disease progress.However,the diastolic function decreased clinically only in the uncompensated period.The systolic function of the right ventricle injured earlier than that of the diastolic function in chronic cor pulmonale patients.It is suggested that AQi technique can reflect the right ventricular function exactly and in real time.更多还原