【摘要】 研究了隐丹参酮与氨、甲胺、乙胺等有机胺的作用。发现丹参酮二氢呋喃环部分在氨及NaOH的作用下发生亲核开环 ,且亲核加成反应与开环反应协同进行。与甲胺、乙胺等有机胺作用则分别生成丹参酮的咪唑环及唑环衍生物。探讨了可能的反应历程更多还原

【Abstract】 Reactions of tanshinones with NH 3,CH 3NH 2,C 2H 5NH 2 and NaOH were investigated. The dihydrofuran ring moiety of tanshinones can be opened by nucleophilic attack in NaOH or NH 3 solutions. In CH 3NH 2 or C 2H 5NH 2 solution, cryptotanshinone form imidazole ring or oxazole ring derivatives of tanshinones respectively. Possible reaction mechanisms were discussed.更多还原