【摘要】 目的　探讨柞蚕丝生产环境对工人呼吸系统的损害。方法　对绢绸厂作业生产环境进行了真菌学调查 ,并对 197名柞蚕丝加工工人及 40名不接触尘毒的对照工人进行了呼吸系统症状的询问调查 ,胸部X线检查及抗芽枝霉和抗交链孢霉抗体的测定。结果　柞蚕丝加工工人各工序真菌数量较对照现场明显增高 ,其优势菌种为芽枝霉及交链孢霉 ;柞蚕丝加工工人呼吸系统症状阳性率明显高于对照组 ,并有 4例X线胸片出现片状炎性影 ,15人经常出现发热症状。柞蚕丝加工工人血清中抗芽枝霉和抗交链孢霉抗体均显著高于对照组。结论　芽枝霉和交链孢霉可能是柞蚕丝生产环境引起过敏性呼吸系统疾病的致病因子更多还原

【Abstract】 Objective To study the effects of tussah silk processing on the respiratory system of workers.Methods Environmental mycological survey was conducted in the tussah silk processing procedures. Investigation of respiratory symptoms and chest X ray examination were also carried out in 197 tussah silk processing workers and 40 control workers. Serum of workers were analized by ELISA. Results Fungal numbers in tussah silk processing procedures were much higher than those in the control environments. Cladosporium and alternaria were the leading strains of fungi in tussah silk processing procedures. The rates of respiratory symptoms in tussah silk processing workers were higher than those in the control workers, and 4 workers showed inflammation in chest X ray findings and 15 workers often had fever. The serum antibodies to cladosporium and alternaria in tussah silk workers were much higher than those in the control workers.Conclusion Cladosporium and alternaria might be the pathogens of occupational allergic respiratory diseases in tussah silk processing workers.更多还原