【摘要】 应用超滤浓缩技术对白喉毒素培养液进行澄清过滤和超滤浓缩 ,已经早已为生产厂家所使用。但是 ,超滤膜的通透性下降很快 ,使膜的使用期限大大缩短 ,生产成本较高。因此在试验过程中 ,注重摸索超滤过程的中间控制以及超滤结束后的清洗方法 ,特别是使用 0 5mol/LNaOH +2 0 0 ppm次氯酸钠作为清洗剂 ,在超滤结束以后对滤膜进行彻底的恢复性清洗 ,可以使澄清和浓缩过滤速度分别达到平均 77L/M2 ·h和 75L/M2 ·h ,回收率分别达到93 1%和 92 8% ,使滤膜的滤过性能 (NWP)基本恢复到滤前水平更多还原

【Abstract】 the application of ultra filtration is described to clarify and filtrate to concentrate Diphtheria toxin in this report.since penetration efficiency was declined quickly,the duration of membrane usage was shortened and its cost was increased.The special attention needs to be paid to intermediate control and washing after completion ultra filtration.It was first time to apply combination of 0.5 mol/L NaOH and 200 ppm sodium hypochlorous acid as a washing solution.On recovery purpose,the used membranes must be washed thoroughly.The filtration properties can be basically recovered as those of a new membrane.In addition,the clearance parameters such as 77 L/M 2·h for a recovery 93.1% and 75 L/M 2·h for 92.8% were under investigation respectively.更多还原