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支原体感染与慢性鼻窦炎及鼻息肉相关关系的初步研究

A Preliminary Study on Relationship between Mycoplasma Infection and Pathogenesis of Chronic Sinusis or Nasal Polyps

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【作者】 华小阳; 崔永华; 高起学; 刘秋润; 李明刚; 卢运萍;

【Author】 Hua Xiaoyang,Cui Yonghua, Gao Qixue et al Department of Otolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030

【机构】 华中科技大学同济医学院附属同济医院耳鼻咽喉科; 华中科技大学同济医学院附属同济医院妇产科; 华中科技大学同济医学院附属同济医院;

【摘要】 运用单克隆抗体免疫荧光法分别检测 5 4例鼻窦炎 (其中 3 8例鼻窦炎并鼻息肉、 16例单纯性鼻窦炎 )和 2 0例单纯性鼻塞患者 (对照组 )鼻腔鼻窦支原体感染情况 ,旨在探讨支原体在慢性鼻窦炎和鼻息肉发病中的作用。结果发现鼻窦炎 ( S)组、鼻息肉 ( SP)组、单纯性鼻窦炎 ( SS)组和对照 ( CG)组支原体检出率分别为 4 4 %、 5 7.9%、 12 .5 %和5 %。S与 CG组、 SP与 SS组、SP与 CG组间均有显著性差异。认为支原体感染可能是慢性鼻窦炎、鼻息肉发病、迁延和复发的又一重要因素。

【Abstract】 In order to explore the role of mycoplasma infection in the pathogenesis, recurrence and deferment of chronic sinusitis and nasal polyps, the presence of mycoplasma was detected in 54 cases of chronic sinusitis (including 38 cases of chronic sinusitis with nasal polyps and 16 cases of simple sinusitis without nasal polyps) and 20 cases of simple snuffle as the control group (including chronic hypertrophic rhinitis and nasal septal deviation without sinus infection). The results showed that the detective rate of mycoplasma in 54 cases of chronic sinusitis (S), 38 cases of sinusitis with polyps (SP), 16 cases of simple sinusitis (SS) and the control group (CG) was 44 %, 57.9 %, 12.5 % and 5 % respectively. There was statistical difference in positive rate between S/CG, SP/SS and SP/CG, but there was no significant difference between SS and CG. It was concluded that mycoplasma might be another important factor in the pathogenesis, recurrence and deferment of chronic sinusitis and nasal polyps.

【关键词】 支原体; 慢性鼻窦炎; 鼻息肉;
【Key words】 mycoplasma; sinusis, chronic; nasal polyps;
  • 【文献出处】 同济医科大学学报 ,Acta Universitatis Medictnae Tangji , 编辑部邮箱 ,2001年05期
  • 【分类号】R765.41
  • 【被引频次】11
  • 【下载频次】51
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