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抗凝水溶液药效学动物实验

Pharmacological Effects of the Kangning Shui Solution on Animals

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【作者】 张革杨学成范晓东

【Author】 Zhang Ge, Fan Xiaodong, Yang Xuecheng (Department of Pharmacology, Shenyang Medical College, Shenyang 110031 )

【机构】 沈阳医学院医学基础部药理学教研室辽宁省糖尿病治疗中心住院部 沈阳110031沈阳110031沈阳医学院99级临床医学班沈阳110015

【摘要】 目的 观察抗凝水溶液对小鼠出、凝血时间及对大鼠血栓形成的影响。方法 用断尾法测定其出血时间 ,用采血法测定其凝血时间 ,用颈动脉及颈静脉旁路法测定其抗血栓作用。结果 抗凝水溶液对大鼠血栓形成有明显的抑制作用 ,对小鼠出血和凝血时间明显延长。结论 抗凝水溶液是一种有效抗凝血药物。

【Abstract】 Objective To observe the effects of Kangning Shui Solution on the thrombosis of rats, the hemorrhage time and coagulation time of mice. Methods (1) To observe the inhibitory action of Kangning Shui Solution on the thrombosis by the carotid and the jugular bypath. (2) To test the hemorrhage time of mice by cutting tail. (3) To test the coagulation time of mice by drawing blood. Results Kangning Shui Solution has obvious inhibition on the thrombosis of rats, extension on the hemorrhage time and the coagulation time of mice. Conclusion Kangning Shui Solution is one of the efficacious drugs on anticoagulation.

【关键词】 出血凝血血栓抗凝水溶液
【Key words】 hemorrhagecoagulationthrombosisKangning Shui Solution
  • 【文献出处】 沈阳医学院学报 ,Journal of Shenyang Medical College , 编辑部邮箱 ,2001年03期
  • 【分类号】R285.5
  • 【下载频次】55
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