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电刺激束旁核对猫丘脑后核群内脏痛放电的影响

Effects of Electrically Stimulating Parafascicular Nucleus on Visceral Pain Discharges in Posterior Group of Thalamic Nuclei in Cat

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【作者】 商丽宏; 吴敏范; 白纯哲;

【Author】 Shang Lihong, Bai Chunzhe, Wu Minfan (Department of Physiology, Shenyang Medical College, Shenyang 110031)

【机构】 沈阳医学院医学基础部生理学教研室!沈阳110031; 辽宁省计划生育科学研究院科技开发中心!沈阳110031;

【摘要】 目的 研究束旁核在痛觉调制中的作用。方法 以电刺激猫内脏大神经在丘脑后核群诱发的单位放电作为内脏痛指标 ,应用细胞外玻璃微电极记录技术及条件 -检验刺激技术。结果 束旁核对丘脑后核群内脏痛放电的影响主要表现为抑制作用 ,抑制作用形式分为即时抑制、延迟抑制和持续抑制。结论 束旁核参与内脏痛的调制 ,主要为抑制内脏痛

【Abstract】 Objective To research the effects of parafascicular nucleus (Pf) on visceral pain discharges. Methods As an index of visceral pain, the discharges of the neurons in the posterior group of thalamic nuclei (PO), evoked by stimulating greater splanchnic nerve (GSN) in 15 cats, were investigated extracellularly. The effects of Pf on the unit discharges were studied with test-conditioning stimulation techniques. Results The effect of Pf upon the neuron discharges in PO: the neuron discharges in PO, caused by excitation of GSN (test stimulus), were mainly depressed. The inhibitory modes of Pf can be classified into three kinds: prompt inhibition, delayed one and continued one. Conclusion Pf may be involved in regulation of visceral pain, mainly in analgesia of visceral pain.

  • 【文献出处】 沈阳医学院学报 ,Journal of Shenyang Medical College , 编辑部邮箱 ,2001年01期
  • 【分类号】R338
  • 【下载频次】25
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