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L-精氨酸对肾性高血压心肌肥厚大鼠左室超微结构的影响

The effects of L-Arg on the ultrastructure of left ventricle hypertrophy in rats with renovascular hypertension

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【作者】 尹时华; 魏劲波;

【Author】 Yin Shihua,Wei Jinbo.Depatment of physiology,Xianning medical college,Xianning Hubei 437100

【机构】 咸宁医学院生理教研室; 湖北医科大学生理学教研室 437100;

【摘要】 目的 观察 L -精氨酸 (L - Arg)对肾血管性高血压心肌肥厚大鼠左室肌超微结构的影响。 方法  L - Arg治疗高血压心肌肥厚大鼠 8周后处死 ,镜检左室心肌亚细胞结构改变。 结果 经 8周治疗后可见 L - Arg治疗组心肌细胞肌丝排列整齐、核规则、核仁清晰、线粒体形态结构正常。 结论  L -Arg能有效保护心肌亚细胞结构。

【Abstract】 Objective To study the effects of L-Arg on the ultrastructure of left ventricle hypertrophy in rats with renovascular hypertension. Methods After treatment of L-Arg 8 weeks the rats with renovascular hypertension were killed and the subcellular structure of their myocardia were examined by electronic microscopy. Results In the L-Arg therpeutic group the myofilament were arranged in good order,nucleuses were regular,nucleole were clear and structure of mitochondrioia were normal. Conclusion There was a protection for the ultrastructure of myocardia,as the rats with renovascular hypertension were cured by L-Arg.

  • 【文献出处】 实用心脑肺血管病杂志 ,Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease , 编辑部邮箱 ,2001年01期
  • 【分类号】R544.1
  • 【下载频次】29
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