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针刺对含apoEε4基因AD患者P300认知电位的影响
The Influence of Acupuncture on Cognitive Evoked Potential P300 in AD Patients with ApoEε4 Gene
【摘要】 目的 观察针刺对含 apo Eε4基因 AD患者 P30 0 认知电位的影响。方法与结果 把 P30 0 引入针刺治疗 AD的研究领域 ,与正常人比较 ,含 apo Eε4基因的 AD患者其认知电位 P30 0 的 N2 ,P3潜伏期明显延长 ,波幅明显降低。针刺有明显兴奋 AD患者认知电位 P30 0 的作用。结论 P30 0 可作为 AD的诊断与疗效评定指标
【Abstract】 Purpose To observe the influence of acupuncture on cognitive evoked potential P 300 in AD patients with apoEε4 gene.Methods and Results P 300 was introduced into the research on acupuncture treatment of AD. Cognitive evoked potential P 300 N 2, P 3 latent period was significanlty prolonged and their amplitudes were significantly reduced in AD patients with apoEε4 gene as compared with normal persons. Acupuncture had a marked arousing effect on cognitive evoked potential P 300 in AD patients.Conclusion P 300 can be used as an index for the diagnosis of AD and the evaluation of the curative effect on it.
【Key words】 Alzheimer’s Disease; Acupuncture therapy; Apolipoprotein; Allele Evoked potential/P 300;
- 【文献出处】 上海针灸杂志 ,Shanghai Journal of Acuuncture and Moxibustion , 编辑部邮箱 ,2001年06期
- 【分类号】R245
- 【被引频次】5
- 【下载频次】102