【摘要】 目的　通过对伽玛刀治疗计划中照射容积和靶区容积的差异比较 ,进行剂量计划的优选 ,以准确设定照射范围 ,减少治疗后的并发症。方法　将 86 0例病人的靶区容积、照射容积及靶区 (照射 )容积直方图进行比较和统计分析。结果　中位数百分比合格率最高为脑膜瘤 ,其次为垂体瘤 ,听神经瘤和AVM ,最低为淋巴瘤。结论　进一步缩小靶区容积和照射容积差异 ,对提高伽玛刀剂量计划设计的最优化、减少并发症有较大意义更多还原

【Abstract】 Purpose To optimize the individual Gamma Knife dose planning by the comparative study between prescription volume and target volume. Methods The target volume,presciption volume and their histogram of eight hundred and sixty patients had been compared and statistically analysed. Results The median ratio of prescription volume and target volume had been detailed.That of meningioma ranked first.Pituitary adenoma,acoustic neurinoma and AVM ranked second and third.That of lymphoma was the lowes t.Three hundred and eighty five cases had been followed up.Lesions of 154 cases regressed and disappeared,of 192 cases had partial shrinkage(>50%),of 27 cases (<50%)and of 13cases enlarged. Conclusions To abate the differences between prescription volume and target volume may improve the optimization of dose planning and decreased the complications after radiosurgery.更多还原