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超声心动图对高血压病人左室舒张功能再评价

Reevaluation of Left Ventricular Diastolic Function in Essential Hypertension Patients by Echocardiography

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【作者】 胡瑞; 张象贤; 王亚芬; 刘国平; 龚辉; 沈伟; 徐浩仁;

【Author】 HU Rui,ZHANG Xiang xian,WANG Ya fen,LIU Guo ping,GONG Hui,SHENG Wei,XU Hao ren (Department of Cardiology,Jinshan Hospital,Fudan University,Shanghai 200540)

【机构】 复旦大学附属金山医院心内科!上海200540; 复旦大学附属金山医院心内科!;

【摘要】 目的 探讨超声心动图对高血压 (EH)病人左室舒张功能评价价值。方法  140例EH病人分为左室肥厚组 47例 ,非左室肥厚组 93例 ,予二维超声心动图及Doppler频谱检测 ,并与 2 5例正常人对照。 结果 在正常组和NLVH组 ,E/A比值、PA值和PAi有显著差异 ;IVRT、LAD在 3组之间有显著差异 ;EF %值在NLVH组与正常组相似 ,与LVH组差异有统计学意义。结论 PA、PAi增高、E/A比值减低、IVRT延长和LAD增大是EH左室舒张功能减低的敏感指标。EF值变化提示EH早期左室收缩功能并未受到影响 ,随着疾病进展而逐步受损。

【Abstract】 Purpose To assess left ventricular diastolic function in the patients with essential hypertension. Methods 25 normotensives,93 hypertensiives without hypertrophy (NLVH) and 47 with hypertrophy (LVH)(LVMI,left ventricular mass index >124 g/m 2 in males and 110 g/m 2 in females) underwent 2DE and Doppler echocardiography. Results The ratio of early to late peak velocity (E/A) was 1.21±0.24 in normotensives and 1.03±0.23 in NLVH patients( P <0.01);reversed pulmonary venous flow at atrial systole PA wave was (32.7±7.5) vs (38.9±8.7)cm/s ( P <0.01) in normotensives and in NLVH patients respectively.The isovolumic relaxation time (IVRT) and left atrial dimension (LAD) have significant differences in three groups ( P <0.05-0.001).EF value was similar between normotensives and NLVH patients,but it was lower in LVH patients ( P <0.01). Conclusions E/A ratio,PA wawe,Pai,IVRT and LAD are sensitive parameters indicating mild diastolic left ventricular dysfunction.Systolic left ventricular function has no change in NLVH patients.

  • 【文献出处】 复旦学报(医学科学版) ,Journal of Shanghai Medica(University) , 编辑部邮箱 ,2001年01期
  • 【分类号】R544.1
  • 【被引频次】6
  • 【下载频次】52
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