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中药治疗幽门螺杆菌相关性胃炎的随机对照试验

A Randomized Controlled Trial of Chinese Herbal Medicine for Helicobacter Pylori Associated Chronic Gastritis

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【作者】 黄穗平余绍源罗云坚钟涌涛陈培琼张学斌尚文璠石灵春

【Author】 HUANG Suiping, YU Shaoyuan, LUO Yunjian, ZHONG Yongtao, CHEN Peiqiong, ZHANG Xuebing, SHANG Wenpan, SHI Lingchun (Dept.of Internal Medicine,Second Affiliated Hospital,Guangzhou University of TCM,Guangzhou 510120,China)

【机构】 广州中医药大学第二附属医院内科!广州510405广?

【摘要】 【目的】研究胃炎清胶囊 (由黄连、蒲公英、佛手、三七、黄芪等中药组成 )治疗幽门螺杆菌 (HP)相关性慢性胃炎的临床疗效。【方法】采用随机对照方法 ,将 12 6例患者按 2∶1随机分为 2组 ,其中治疗组 83例 ,对照组 4 3例 ,治疗组口服胃炎清胶囊 ,对照组口服德诺 (枸橼酸铋 ) ,6周为 1疗程。【结果】治疗组的临床症状 (如上腹胀痛等 )改善、胃镜炎症改善的有效率、病理组织学炎症改善及HP清除率等疗效均优于对照组 ,并以脾胃湿热型疗效最好。【结论】胃炎清胶囊适用于幽门螺杆菌相关性慢性胃炎患者 ,尤适用于脾胃湿热型者

【Abstract】 Objective To assess the therapeutic effects of Weiyanqing Capsule(WC) on Helicobacter pylori associated chronic gastritis (HPACG). Methods A randomized controlled trial was carried out.One hundred and twenty_six cases of HPACG were randomly allocated to treatment group (Group A,83 cases) and control group (Group B,43).The treatment group was treated with WC orally and the control group with bismuth citrate,and the treatment course last 6 weeks. Results The clinical symptoms in the treatment group such as epigastric distension,anorexia were much improved as compared with the control group.So did the findings of gastroscopy and histopathology.The elimination rate of Helicobacter pylori was higher than that in the control group.The therapeutic effect of WC for the patients with spleen_stomach heat_dampness syndrome was the best. Conclusion WC is effective for HPACG patients and especially for those with spleen_stomach heat_dampness syndrome.

  • 【文献出处】 广州中医药大学学报 ,Journal of Guangzhou University of Traditional Chinese Medicine , 编辑部邮箱 ,2001年01期
  • 【分类号】R285.5
  • 【被引频次】38
  • 【下载频次】327
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