【摘要】 植物正在成为疫苗的新型生物反应器之一。本文较全面地介绍了当前转基因植物疫苗研究的概况，详细综述了各种转基因植物疫苗的研究进展，指出了转基因植物疫苗研究面临的主要问题及其发展的新趋势。更多还原

【Abstract】 Plants are becoming bioreactors for production of vaccines.In this review, expression of many antigens from pathogenic microorganisms in plants and immunogenicity of the plant-derived vaccines in human,mice and pigs are discussed in detail based on recent studies on transgenic plant-derived vaccines.Results of these studies show that the heterogenous antigens can be produced in plants in their native,immunogenic forms and human,mice and pigs can response to these antigens.These results indicate the potential usefulness of plants for vaccine production.However several problems remain,including development of more suitable plant systems to produce vaccines, low expression level of antigenic proteins in plant tissues,harmful effect on plant development due to accumulation of antigen proteins in plant,relatively low efficiency of the plant-derived vaccines.So future research needs to be directed towards solving these problems.更多还原