【摘要】 观察中药对大鼠肠系膜血管结扎术后所致肠粘连的防治作用。给药组分为通腑攻下组、活血化瘀组、通腑攻下加活血化瘀组 3个组。 96h后开腹观察肠粘连程度和肠腔扩张、水肿、肠壁各层血管扩张、出血、肠系膜及间膜炎症反应等病理变化。结果 :与模型组比较 ,通腑攻下加活血化瘀组能明显减轻肠粘连 ,肠腔扩张、水肿 ,肠壁各层血管扩张、出血 ,肠系膜及浆膜炎症。结论 :通腑攻下加活血化瘀中药有防治因缺血所致肠粘连和减轻肠损伤作用。更多还原

【Abstract】 The effects of TCM drugs on rat postoperative intestinal adhesion were observed in this experimental study. Wistar male rats were used to induce intestinal adhesion by ligating mesenteric blood vessels. The rats with postoperative intestinal adhesion were then divided into the model control group, and several dfferent treating groups to which TCM drugs for purging the bowls (PB), activating blood circulation (ABC) and PB plus ABC were given respectively. After 96 hours, laparotomy was performed on all the animals in the experiment for the observation of pathological changes, including intestinal adhesion, intestinal distension and edema, angiectasis and hemorrhage in each enteric layer, and inflammation of mesentery and serous coat. The results showed that compared with the model control group, there was a significant relief of intestinal adhesion, intestinal distension and edema, angiectasis and hemorrhage in each enteric layer, and inflammation of mesentery and serous coat in the animals in the PB plus ABC group ( P <0.01). Therefore, it can be concluded that the PB plus ABC formula has curative effects on intestinal adhesion and intestinal injuries caused by intestinal ischemia.更多还原