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An improved coupling reaction for the preparation of pyridylethynyl benzonitrile compounds

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【Author】 WANG Zhiyong, LIN Wenbin, JIANG Chao & QUO Qingxiang1. Department of Chemistry, University of Science & Technology of China, Hefei 230026, China;2. Deparment of Chemistry, Brandeis University, Waltham, MA02454, USA

【摘要】 <正>An improved coupling reaction between aromatic ring and acetylene triple bond catalyzed by palladium (0) catalyses for the preparation of pyridylethynyl benzoni-trile compounds is described. Efforts were made to improve the reaction by changing different reaction conditions and it was found that the solvent is one important factor in this situation.

【Abstract】 An improved coupling reaction between aromatic ring and acetylene triple bond catalyzed by palladium (0) catalyses for the preparation of pyridylethynyl benzoni-trile compounds is described. Efforts were made to improve the reaction by changing different reaction conditions and it was found that the solvent is one important factor in this situation.

【基金】 This work was supported by the National Natural Science Foundation of China (Grant No. 50073021)
  • 【文献出处】 Chinese Science Bulletin ,科学通报(英文版) , 编辑部邮箱 ,2001年19期
  • 【分类号】O625
  • 【下载频次】16
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