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导数光谱法测定微乳中维生素C的含量

DERIVATIVE SPECTROPHOTOMETRIC DETERMINATION OF VITAMIN C IN MICROEMULSIONS

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【作者】 张正全; 陆彬; 杨秀岑;

【Author】 ZHANG Zheng quan,LU Bin,YANG Xiu cen School of Pharmacy, West China University of Medical Sciences, Chengdu 610041,China

【机构】 华西医科大学药学院!四川成都610041;

【摘要】 目的 :探讨微乳中药物的测定方法。方法 :分别利用二阶及三阶导数光谱测定了维生素C(VitC)的O/W及W/O型微乳中VitC的含量。结果 :平均回收率及精密度分别达到 98.1% ,RSD % =0 .6 2 (n =12 ) ;99.0 % ,RSD % =0 .5 2 (n =12 )。结论 :该法简便 ,适合VitC微乳的含量测定。为保证结果可靠 ,样品需作前处理

【Abstract】 OBJECTIVE:To investigate the method for determination of vitamin C in microemulsions. METHODS:The content of vitamin C in O/W microemulsions and W/O microemulsions was determined by second order derivative spectrophotometry and third order derivative spectrophotometry, respectively.RESULTS:The recovery and accuracy are 98.1%, RSD%=0.62 (n =3) and 99.0%, RSD%=0.52 (n =3), respectively.CONCLUSION:This method has the advantage of simplicity and is suitable for determination of the content of vitamin C in microemulsions.

  • 【文献出处】 华西药学杂志 ,West China Journal of Pharmaceutcal Sciences , 编辑部邮箱 ,2001年01期
  • 【分类号】R927.2
  • 【被引频次】13
  • 【下载频次】163
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