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克霉唑与茜素红的荷移反应研究
Study of the Charge Transfer Reaction between Clotrimazolum and Alizarin Red
【摘要】 本文用分光光度法研究并确定了克霉唑与茜素红的荷移反应条件。在丙酮 水介质中形成 1∶1配合物 ,其λmax=5 2 5nm ,克霉唑浓度在 0~ 10 0 μg·mL-1范围内呈线性关系 ;表观摩尔吸光系数为 8 7× 10 3L·mol-1·cm-1,相对标准偏差为 1 2 2 % (n =6) ,回收率符合要求。
【Abstract】 The charge transfer reaction between clotrimazolum and alizarin red was studied spectrophotometrically.The reaction was achieved with good results in water-acetone solution.The apparent molar absorptivity is 8 7×10 3 L·mol -1 ·cm -1 at 525 nm.The Beer′s law was obeyed in the range of 0-100 μg·mL -1 of clotrimazolum.The composition of the complex is 1∶1.The proposed method has been applied successfully to the determination of clotrimazolum tablets.
【关键词】 荷移反应;
克霉唑;
茜素红;
分光光度;
【Key words】 Charge transfer reaction; Clotrimazolum; Alizarin red; Spectrophotometry;
【Key words】 Charge transfer reaction; Clotrimazolum; Alizarin red; Spectrophotometry;
- 【文献出处】 光谱学与光谱分析 ,Spectroscopy and Spectral Analysis , 编辑部邮箱 ,2001年05期
- 【分类号】R914
- 【被引频次】7
- 【下载频次】83