【摘要】 目的 :探讨各种完全胃肠外营养 (TPN)对胆源性胰腺炎胆囊收缩及胆汁酸成分改变的作用。　方法 :选择胆源性胰腺炎住院病人共 86例 ,在常规治疗相同的基础上 ,随机分成四组 ,TPN支持分别为仅用糖盐水 (GNS组 )、糖盐水加用 7%凡命 (VM组 )、糖盐水加用 2 0 %英脱利匹特 (IL组 )、糖盐水加用 7%凡命及 2 0 %英脱利匹特(VM +IL组 )。B超测量胆囊体积及计算最大胆囊排空率 (MGER) ,气相色谱法检测胆汁游离脂肪酸 (FFA)。　结果 :发现VM +IL组及VM组与GNS及IL组比较MGER显著升高 ,差异显著 (P <0 .0 5 ) ;VM +IL组及IL组与GNS组比较 ,各种胆汁FAA构成比较差异显著 (P <0 .0 5 )。　结论 :TPN中加入VM +IL或VM会促进胆囊排空 ,加入VM +IL或IL会减轻胆汁FFA变化程度 ,均对胆石形成或增大可能有预防作用更多还原

【Abstract】 Objectives:To observe the effects of total parenteral nutrition(TPN) on gallbladder contraction and bile acid ingredient changes in the patients of biliogenic pancreatitis. Methods:86 patients of biliogenic pancreatitis on routine treatment were divided into 4 groups randomly,and TPN supports were given.Glucose in normal saline(GNS) was used only in the first group,7% Vamin(VM)+GNS(VM+IL) used in the second group,20% Interlipid(IL)+GNS(VM+IL) used in the third group and 7%VM+20% IL+GNS used in the fourth group.The volume of gallbladder and the maximum gallbladder emptying rate(MGER) were measured by type B ultrasonograph.The free fatty acid(FFA) in bile was detected by gas chromatography. Results:MGERs were significantly higher in the second and fourth group than in the first and third group( P <0.05).There were significantly differences of free fatty acid ingredients in bile between the groups using VM or VM+IL and the group using GNS( P <0.05). Conclusions:VM+IL or VM in TPN can promote the gallbladder emptying. VM+IL or IL in TPN can decrease the changes of bile FFA.They may prevent the formation or enlargement of gall stone.更多还原