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C肽释放反应类型在糖尿病中的应用

Application of Reaction Type of C-peptide Release Test in Diabetes Mellitus

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【作者】 陈栋段文若何娟卢振芳

【Author】 CHEN Dong, DUAN Wen-ruo, HE Juan, et al. (Qingdao Municipal Hospital, Qingdao 266011, China)

【机构】 青岛市立医院!山东青岛266011

【摘要】 为探讨C肽 (CP)释放试验及其反应曲线类型 ,在评价糖尿病 (DM )患者胰岛 β细胞功能、指导选择治疗方案等方面的作用 ,本文对 6 7名正常人和 2 17例DM患者行C肽释放试验测定 ,并对结果进行比较分析。结果表明 ,CP释放试验较好地反映胰岛 β细胞功能状态 ,餐后CP峰值≥ 0 .6nmol/L ,它可作为DM患者是否使用口服降糖药物治疗的界限 ,但应结合分析CP释放反应类型以选择调整治疗方案。CP释放试验在评价胰岛 β细胞功能、指导分型和选择治疗方案方面有非常重要的作用。

【Abstract】 The article is to confirm the effect of C-peptide release test and types of release reaction in appraisal of pancreas function of β-cell and selection of treatment for diabetes mellitus (DM) patients. The serum C-peptide release test of 67 normal controls and 217 DM patients were determined by RIA, and the results were analyzed and compared. C-peptide release test can reflect the pancreas function of β-cell better, the peak of C-peptid≥0.6nmol/L after lunch can be the limit of whether to reduce the level of blood glucose only by oral drug. We should adjust the treatment through analyzing the type of C-peptide release reaction. C-peptide release test is very important in evaluating the pancreas function of β-cell, classifying the type of DM and selecting the treatement.

  • 【文献出处】 标记免疫分析与临床 ,Labeled Immunoassays and Clinical Medicine , 编辑部邮箱 ,2001年01期
  • 【分类号】R587.1
  • 【被引频次】8
  • 【下载频次】105
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