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差示分光光度法测定盐酸异丙嗪糖浆中盐酸异丙嗪的含量

Determination of Promethazine hydrochloride Syrup by Differential Spectrophotometry

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【作者】 张桂芳王复馨

【Author】 Zhang Guifang, Wang Fuxin Shangdong Provincial Hospital, Jinan 250021, P. R. China

【机构】 山东省立医院山东省立医院 济南市 250021济南市 250021

【摘要】 目的:建立应用差示分光光度法测定盐酸异丙嗪糖浆中盐酸异丙嗪的含量。方法:采用差示分光光度法进行测定,测定波长337nm。结果:盐酸异丙嗪在20~60mg·ml-1范围内线性关系良好,其平均回收率为99.5%,RSD为0.4%(n=6)。结论:本法操作简便,快速,结果准确。

【Abstract】 Objective: A quantitative method was established for the content determination of promethazine hydrochloride syrup by differential spectrophotometry. Method: Differential spectrophotometry was employed for content determination of promethazine hydrochloride with detecting wavelength of 337 nm. Results; The standard curve presented linear in the concentration range form 20 to 60 mg·2ml-1. The average recovery was 99. 5 % (RSD = 0.36%). Conclusion: This method is simple, rapid and accurate.

  • 【文献出处】 中国药师 ,China Pharmacist , 编辑部邮箱 ,2000年06期
  • 【分类号】R927.2
  • 【被引频次】6
  • 【下载频次】33
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