【摘要】 目的　了解肠球菌对常用抗生素的耐药性 ,为临床肠球菌的治疗提供参考及指导。方法　采用微量稀释药敏法 ,对 3年临床分离的 76 9株肠球菌进行药敏测试。结果　 76 9株肠球菌中粪肠球菌、屎肠球菌、耐久肠球菌分别占 2 4.9%、2 3.9%、5 1.2 %。药敏测试结果显示肠球菌对庆大霉素、林可霉素、复方新诺明、苯唑西林的耐药率分别高达 95 .8%、94.4%、92 .2 %、85 .2 % ;对环丙沙星、利福平、头孢曲松、红霉素的耐药率为5 2 .7%、6 1.4%、6 8.0 %、6 8.8% ;而对青霉素、氨苄西林、万古霉素的耐药率低为 2 3 .2 %、17.6 %、3.0 %。结论　肠球菌对庆大霉素、林可霉素、复方新诺明、苯唑西林存在严重的耐药。万古霉素的耐药率低 ,仅为 3.0 %。屎肠球菌与粪肠球菌和耐久肠球菌比较耐药较为严重更多还原

【Abstract】 OBJECTIVE To understand the situation of drug resistance of enterococcus to common antibiotics,furthermore,to provide the reference and guideline for the treatment of enterococcus infection.METHODS Seven hundred and sixty nine strains of enterococcus from isolating culture of clinical samples were measured by drug microdilution test.RESULTS Enterococcus faecalis,E.faecium,E.durans accounted for 24.9%,23.9% and 51.2% ,respectively among 769 strains of enterococcus.The resistance rate of enterococcus to gentamycin,lincomycin,SMZco,oxacillin was 95.8%,94.4%,92.2%,85.2%;to ciprofloxacin,rifampicin,ceftriaxone,erythromycin was 52.7%,61.4%,68.0%,68.8%;to penicillin G,ampicillin,vancomycin was 23.2%,17.6%,3.0%,respectively. CONCLUSIONS There were no significant changes in drug resistance rate of enterococcus between April 1996 April 1997 and April 1997 April 1998.The E.faecium with higher drug resistance rate to ciprofloxacin,cefalotin,cefazolin and ampicillin than E.faecalis,Streptococcus durans(P<0.05 or P<0.01).更多还原