【摘要】 对新药依替米星合成中的相关产物进行了分离和鉴定 ,得到了两个新的庆大霉素 C1 a乙基化衍生物。通过化学降解、质谱和核磁共振的测定和分析 ,证实它们的化学结构分别为 3″- N-乙基庆大霉素 C1 a和 1,3″-二 - N-乙基庆大霉素 C1 a。它们具有弱的抗菌活性更多还原

【Abstract】 Related products of etimicin were seperated and identified by means of chemical degradation, MS and NMR. They are two new derivatives of gentamicinC 1a : 3″ N ethylgentamicinC 1a and 1,3″ di N ethylgentamicinC 1a , respectively. They possessed weak antibacterial activity.更多还原