【摘要】 目的　探讨影响涎腺腺样囊性癌 (adenoidcysticcarcinoma ,ACC)预后的各因素。方法　对 196 0～ 1985年间收治并随诊 10年以上的ACC 112例进行临床病理分析 ,对各项指标采用乘限法(productlimit) ,估计各时点的生存率 ,并绘制Kaplan Meier生存曲线 ,同时序检验 (logranktest)各组间差异。全部资料用生存分析软件完成。结果　 10年随诊临床与病理观察 ,计算机对数据进行单因素和多因素的分析 ,处理结果表明 ,年龄小于 5 0岁、临床分期属早期 (Ⅰ、Ⅱ期 )、病理类型为腺样或小管型、神经未受侵的患者预后优于年龄在 5 0岁以上、病变部位于颌下腺、临床分期属于晚期 (Ⅲ、Ⅳ期 )、病理类型为实体型、神经受侵者。结论　患者年龄、病变部位、临床分期、病理类型、神经受侵与否是影响涎腺ACC预后重要因素更多还原

【Abstract】 Objective To study factors influencing survival rate of adenoid cystic carcinoma (ACC) of the salivary glands. Methods One hundred and twelve cases were followed up for move than ten years and were studied to investigate factors influencing the survival rate of patients. Statistical analysis was performed using a computer program (Survcalc, John Wiley Co.). The data were statistically treated for survival curves according to the kaplan meier method. The log rank tests were employed to assess the statistical significance of various groups. Results The age of the patients younger than 50 years old, early clinical stage, glandular / tubular histological type and tumor without nerve involvement had the best prognosis. Age of the patients older than 50 years old, ACC in the submandibular gland, advanced clinical stage (stage III and IV), solid histological type and tumor with nerve involvement had a poor prognosis. Conclusions Age of the patients, tumour site, clinical stage, histological type and with or without nerve involvement are the important factors influening the prognosis.更多还原