节点文献
中药骨康防治去势大鼠骨丢失的实验研究
Effects of Herb Gukang on Preventing and Treating Bone-loss of Ovariectomized Rats
【摘要】 观察骨康口服液防治通过切除卵巢诱发的绝经后骨质疏松症大鼠模型骨丢失的药效。通过双能X线扫描、血清激素水平测试等实验,结果显示:骨康组大鼠的骨矿含量(BMC)和骨密度(BMD),以及血清中雌二醇(E2)、降钙素(CT)和骨钙素(BGP)的含量均明显高于造模组。提示骨康能够提高去势大鼠的BMC和BMD,纠正大鼠去势后体内E2、CT、BGP水平较低的状况,具有抑制骨吸收和促进骨形成的双重作用。
【Abstract】 This experiment observed the effects of herb “Gukang” on preventing and treating bone-loss of PMOP rat models which made by ovariectomy.By Dual energy X-ray scaning and serum hormone contents test,the results showed that the datas of BMC,BMD,E 2,CT and BGP of “Gukang” group rats higher significantly than OVX group’s all,which suggest that “Gukang” could increase BMC and BMD,institute secretion of E 2,CT and BGP,be of the double-action of suppresing bone-absorption and promoting osteosis.
【关键词】 骨康;
去势大鼠;
防治骨丢失;
实验研究;
【Key words】 Gukang Ovariectomized-rat Prevent and treat bone-loss Experimental research;
【Key words】 Gukang Ovariectomized-rat Prevent and treat bone-loss Experimental research;
【基金】 国家中医药管理局科研基金!编号:95B3211
- 【文献出处】 中国中医骨伤科杂志 ,Chinese Journal of Traditional Medicial Traumatology & Orthopedics , 编辑部邮箱 ,2000年01期
- 【分类号】R285
- 【被引频次】24
- 【下载频次】73