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高龄急性心肌梗塞溶栓治疗的临床研究

Clinical Investigation of Thrombolysis in Elder Patients with Acute Myocardial Infarction

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【作者】 张福春郭静萱毛节明郭晓斌丛玉芳

【Author】 Zhang Fuchun,Guo Jingxuan,Mao Jieming,et al. Division of Cardiology,the Third Hospital of Beijing Medical University,Beijing(100083)

【机构】 北京医科大学第三附属医院

【摘要】 目的 :观察静脉溶栓治疗高龄 (≥ 75岁 )急性心肌梗塞 (AMI)患者的临床疗效。  方法 :高龄 AMI患者 70例 ,经静脉溶栓治疗患者 34例为溶栓组 ,同期未溶栓治疗患者 36例为未溶栓组 ,对比分析两组临床结果。  结果 :溶栓组临床血管再通率为 6 8%。病死率溶栓组为 15 % ,未溶栓组为 2 5 % ;溶栓组中心力衰竭的发生率在冠状动脉再通者中 30 % ,未通者中 5 5 % ,病死率再通者中 4.4% ,未通者中 36 .4%。  结论 :静脉溶栓治疗高龄 AMI可降低病死率 ,减少心力衰竭发生 ,改善预后。

【Abstract】 Objective:To observe the efficacy of the venous thrombolysis in the elder patients with acute myocardial infarction(AMI). Methods:The elder patients with AMI treated in our hospital in recent 3 years were divided into 2 groups.In group Ⅰ,patients were treated with venous thrombolysis and in group Ⅱonly conventional treatment was used.The results of 2 groups were analysed. Results:The clinical repatency rate was 68%,while the mortality was 15% in group Ⅰand 25% in group Ⅱ.There were 32% of patients in subgroup A (the recanalization subgroup in group Ⅰ) developed heart failure and 55% in subgroup B (the nonrecanalization subgroup of group Ⅰ).Among the patients in group Ⅰ,the mortality of the subgroup A was 4 4% and 36 4% in subgroup B. Conclusion:The venous thrombolysis therapy can lower the mortality and improve the prognosis in elder patients with AMI.

【关键词】 心肌梗塞溶栓疗法高龄
【Key words】 Myocardial infarctionThrombolysisElder
  • 【文献出处】 中国循环杂志 ,CHINESE CIRCULATION JOURNAL , 编辑部邮箱 ,2000年03期
  • 【分类号】R542.22
  • 【被引频次】42
  • 【下载频次】44
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