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中药安菌凝胶对狐狸阴道加德纳菌病的实验研究

THE STUDY ON GARDNERELLA VAGANALIS OF FOX WITH ANJUN GELATIN OF CHINESE HERBS

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【作者】 侯朝晖杨景云任力阎新华侯智韬

【Author】 HOU Zhao hui,Yang Jing yun,REN Li, (Air force general hespital,Beijing 100036,China)

【机构】 空军总医院妇产科!北京100036佳木斯大学医学院中国农科院特产研究所吉林市药品检验所

【摘要】 通过对狐狸加德纳菌病 (GVF)阴道菌群分析、阴道光镜和电镜下组织学结构观察认定 ,GVF与人类细菌性阴道病 (BV)同属菌群失调所致 ,并以此为动物模型 ,采用黄芪、苦参、蛇床子、甘草四味中药以新型高分子材料卡波姆 (Carbomer)为赋形剂制成凝胶 ,对其进行体外抑菌实验和不同组方的疗效比较 ,结果显示 :B组方中药制剂 (安菌凝胶 )治疗后的疗效最好 ,并在细胞水平上对中药作为微生态调节剂的机制进行了初步探讨

【Abstract】 GVF and BV were considered to be caused by dysbacterioses through analysis of the foxes viginal bacterium of GVF and observitions of optical and electronic microscope.In the animal models, four kinds of chinese herbs (Radix astragalus,Glycyrrhiza,Radix sophorae flavascens and Fructus cnidii, gelatin was made of the four kinds of the herbe with carbomer)were used for susceptibility in vitro and the treatment results of different combination of herbs were compared. The results show that the best curative effect was group B,and the mechanism that the herbs acted as microecologic regulator was primary discussed in ultrocellar lever.

  • 【文献出处】 中国微生态学杂志 ,CHINESE JOURNAL OF MICROECOLOGY , 编辑部邮箱 ,2000年04期
  • 【分类号】R285
  • 【被引频次】16
  • 【下载频次】142
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