【摘要】 目的　了解重组人生长激素 (rhGH)对手术后病人氮平衡的影响。　方法　在肠全外营养 (TPN)的基础上 ,加用rhGH治疗消化道大中型手术后 10例病人 ,并与同期仅用TPN治疗的 10例病人做对照研究。　结果　 1.2组病人均未获得正氮平衡 ,但GH组氮平衡明显改善 ;术后 5天累积氮平衡GH组显著高于对照组。2 .术后 3天、5天 ,累积尿氮的排出 ,对照组较GH组高 ,二者差别有显著统计学意义。3.术后 1天引流氮的排出、术后 3天累积引流氮的排出及平均每天引流氮的排出 ,GH组均较对照组低 ,但无显著的统计学意义。　结论　在低氮和低热的基础上 ,rhGH能减轻术后病人的负氮平衡。主要是通过减少尿氮的排出而达到节氮效果 ,rhGH对引流氮影响不大。更多还原

【Abstract】 Objective To observe the effects of recombinant human growth hormone(rhGH) on postoperative nitrogen balance. Methods Twenty postoperative patients were randomly divided into two groups. One group received only total parenteral nutrition (TPN) as control, the other group received TPN and rhGH(GH group). Results 1. Both groups did not achieve positive nitrogen balance, but negative nitrogen balance was improved in GH group. Cumulative nitrogen balance of five days of GH group was significantly higher than that of the control group. 2. Cumulative urine nitrogen of three days and five days of the GH group were significantly higher than those of the control group. 3. Drain liquid nitrogen of the GH group was lower than that of the control group , but not significant statistically.Conclusions The study showed that rhGH with low calorie and low nitrogen can attenuate negative nitrogen balance of postoperative patients. RhGH may has positive effects on postoperative patients’ rehabilitation.更多还原