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黄芩茎叶总黄酮调血脂作用研究

Studies on the Blood Lipid Regulating Effects of the Total Flavonoid from Baikal Skullcap (Scutellaria baicalensis) Stem and Leaf

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【作者】 佟继铭刘玉玲符景春

【Author】 Institute of Chinese Materia Medica, Chengde Medical College (Chengde 067000) Tong Jiming, Liu Yuling and Fu Jingchun

【机构】 承德医学院中药研究所!067000

【摘要】 黄芩茎叶总黄酮 (以下简称总黄酮 )是黄芩茎叶的主要有效部位。动物实验结果证明 ,在给大鼠喂以高脂饲料的同时 po总黄酮能明显抑制血清总胆固醇 (TC)、甘油三酯 (TG)和低密度脂蛋白 (L DL- C)的升高。对已经形成高脂血症的大鼠 ,也能明显降低血清 TC、TG、L DL- C的水平及动脉粥样硬化指数 (AI,AI=TC-HDL- C/ HDL- C)。提示总黄酮对大鼠实验性高脂血症有显著的预防和治疗作用

【Abstract】 Blood lipid regulating effects of the total flavonoid (TF) from the stem and leaf of Scutellaria baicalensis Georgi were studied. Experimental results showed that TF could obviously inhibit the elevation of serum total cholesterol (TC). Triglyceride (TG) and LDL C in rats fed with high fatty diet. TF also obviously lowered the levels of TC, TG, LDL C and atherosclerotic index (AI) (TC-HDL C/HDL C) of hyperlipidemic rats. These results suggested that TF had significant preventive and therapeutic effects on experimental hyperlipidemic rats.

【基金】 卫生部资助项目
  • 【文献出处】 中草药 ,CHINESE TRADITIONAL AND HERBAL DRUGS , 编辑部邮箱 ,2000年03期
  • 【分类号】R285
  • 【被引频次】129
  • 【下载频次】405
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