【摘要】 目的：研究模拟缺血、缺氧、缺血缺氧三种条件下肾小管上皮细胞与基底膜的粘附力学特性。材料与方法：利用微管吸吮技术测定肾小管上皮细胞与人工基底膜的粘附力。结果：模拟缺血、缺氧、缺血缺氧三种模型中肾小管上皮细胞与基底膜的粘附力均较正常情况明显降低。结论：不同模拟损伤因素对粘附力的影响不同，其中缺血缺氧组粘附力最小，单纯缺血组的影响较小。这些结果提示，在一定条件下，氧缺乏比缺血情况更能影响肾小管上皮细胞与基底膜的粘附作用。更多还原

【Abstract】 purpose to investigate the adhesive properties of renal tubular epithelial cells on matrigel and compared with the following three cases ischemia、hypoxia and ischemia ＆ hypoxiaI／H ．materials and methods A micropipette aspiration technique was adopted to determine the adhesive mechanics of renal tubular epithelial cells on matrige． results it showed that the adhesion of renal tubular epithelial cells on matrigel was higher than that of those three model further more a different factor was followed by different adhesive mechanic． conclusion the adhesion of I／H is lower the ischemia is higher but all were lower compared with control． It suggested that effect of hypoxia on adhesive properties of renal tubular epithelial cells on matrigel is bigger than that of ichemia．更多还原