【摘要】 目的　观察口服培菲康后血浆氨含量及内毒素水平的变化。方法　采用CCl4 复合因素法建立肝硬化模型 ;鲎试剂法检测血浆内毒素 ;谷氨酸脱氢酶速率法检测血氨。结果　治疗组内毒素及血氨水平均明显低于肝硬化模型组 (P <0 .0 5 ) ,其中预防治疗组血氨低于晚期治疗组 (P <0 .0 1)。结论　益生菌制剂能够降低血浆内毒素及血氨 ,对肝硬化有良好的辅助疗效。更多还原

【Abstract】 WT5”BZ] Objective To observe the change of levels of blood endotoxin and ammonia after feeding probiotics. Methods Fifty male Wistar rats were used to develop the model of liver cirrhosis by injecting carbon tetrachloride hypodermically every 3 days for 8 weeks and were divided into 3 groups.The two treatment groups were fed bifico suspension daily according to different periods.Then the levels of blood ammonia and endotoxin were measured at week 8. Results The levels of ammonia and endotoxin in the treatment groups were significantly lower than those in model group (P<0.05).Conclusion The probiotics can reduce the levels of blood endotoxin and ammonia,adjust the intestinal microflora in cirrhotic rats.So the drug may be used for routine auxiliary treatment on liver cirrhosis. [WT5”HZ]更多还原