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糖尿病脑梗塞患者血浆CD62P测定及意义

Significance of Determination of Plasma CD62P in Celebral Infarction Patients with Diabetes

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【作者】 夏敏张剑平李小雯徐淦泉

【Author】 XIA Min, ZHANG Jianping, LI Xiaowen, et al (Department of Neurology, the First People’s Hospital, Wuxi, Jiangsu 214002)$$$$

【机构】 无锡市第一人民医院神经科!无锡214002

【摘要】 目的揭示血浆血小板膜蛋白CD6 2P对脑梗塞患者血管病变的诊断和预后价值。 方法流式细胞术观察糖尿病与非糖尿病脑梗塞患者CD6 2P的阳性表达率 ,并与健康人作对照。 结果脑梗塞组CD6 2P的阳性表达率高于对照组 (P <0 .0 1) ,且合并有糖尿病组显著高于非糖尿病组 (P <0 .0 1) ;脑梗塞组血小板计数与对照组比较无显著差异。 结论脑梗塞时血小板活化程度明显增高 ,而糖尿病则加剧了这一病理过程的发生。

【Abstract】 Objective To evaluate the diagnostic and prognotic value of CD62P in vascular pathological changes of celebral infarction patients. Methods Compared the positive rate of CD62P with flow cytometry in diabetes and non-diabetes celebral infarction patients. Results The positive rate of CD62P in celebral infarction patients is higher than that of the control group, and the patients with diabetes is higher than patients without diabetes. Compared with control group, the platelet of celebral infarction patients is no statistical difference. Conclusion The activity of platelet in celebral infarction patients is increasing, and diabetes aggravates the occurrence of pathology process.

  • 【文献出处】 上海第二医科大学学报 ,ACTA UNIVERSITATIS MEDICINALIS SECONDAE SHANGHAI , 编辑部邮箱 ,2000年04期
  • 【分类号】R743.33
  • 【被引频次】6
  • 【下载频次】38
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