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某些儿童发疹性疾病与早期肾小管损伤的相关性研究

The study of rash and early renal damage

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【作者】 邹慧承郭十庆徐虹

【Author】 ZOU Hui-cheng 1,GUO shi-qing 1,XU Hong 2(1 The 3rd hospital of Wuhan 430060;2 The 457 hospital of PLA.Wuhan 430012)

【机构】 武汉市三医院儿科!430060解放军第四五七医院儿科!430012

【摘要】 本文采用双抗体夹心酶免疫测定法测定了 85例皮疹伴发热患儿及对照组 80例无皮疹发热上感患儿尿液的视黄醇结合蛋白 (Retinolbindingprotein ,RBP)含量 ,皮疹组患儿尿RBP含量全部高于正常值 ,而对照组患儿尿RBP含量全部在正常范围内 ,二组间经t检验 ,P <0 0 1,有显著性意义。因为尿RBP是早期肾功能损害最敏感而可靠的检测指标 ,所以本资料结果提示皮疹患儿可能有肾损伤

【Abstract】 Urinary retinol binding protein (RBP)was determined in 85 cases of children with rash and fever and 80 cases of children with influenza and fever by enzyme-linked immunosorbent assay.The result revealed that the content of urinary RBP in children with rash and fever was much higher than that of the children with influenza and fever (P<0 01).The data suggested that urinary RBP assay may be a sensitive and reliable index for evaluating of early proximal tubular functional impairment,so the children with rash and fever may have renal tubular funtional lesion.

【关键词】 皮疹视黄醇结合蛋白肾损害尿
【Key words】 RashRetinol conjugated ProteinRenal damageUrine
  • 【文献出处】 皮肤病与性病 ,JOURNAL OF DERMATOLOGY AND VENEREOLOGY , 编辑部邮箱 ,2000年03期
  • 【分类号】R725.9
  • 【下载频次】17
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