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思瑞康与利培酮治疗精神分裂症对照研究
A controlled study on seroquel and risperidone in the treatment of schizophrenic patients
【摘要】 目的 :探讨思瑞康治疗精神分裂症的疗效及副反应。 方法 :以思瑞康与利培酮治疗精神分裂症各 2 0例作对照研究 ,采用阳性症状与阴性症状量表 (PANSS)、不良反应症状量表 (TESS)评定疗效及副反应。 结果 :利培酮组有效率 80 % ,显效率 40 % ;思瑞康组有效率 89% ,显效率 78%。均无明显锥外系反应 ,仅表现为兴奋激越等副反应。 结论 :该两种药对治疗精神分裂症均有确切疗效 ,且安全性相对高 ,思瑞康对症状的改善可能更好
【Abstract】 Objective:To research the therapeutic and side effects of seroquel in the treatment of schizophrenic patients. Method:Twenty schizophrenic patients were treated with risperidone as the controlled group.The efficacy was measured with the positive and negative symptoms scale (PANSS),while the adverse events were determined by the treatment emergent symptoms scale (TESS). Results:The efficacy rate of risperidone was 80%,in which 40% were improved markedly. The efficacy rate of seroquel was 89%, in which 78% were improved markedly. Conclusion:It is suggested that both drugs are effective exactly in the treatment of schizophrenic patients and fewer side effects.Seroquel appears to be more effective in improving psychiatric symptoms.
- 【文献出处】 临床精神医学杂志 ,JOURNAL OF CLINICAL PSYCHOLOGICAL MEDICINE , 编辑部邮箱 ,2000年04期
- 【分类号】R749.3
- 【被引频次】39
- 【下载频次】63