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母乳中生长抑素的测定及其意义的探讨

Determination of somatostatin level in breast milk and its clinical significance

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【作者】 黄萍; 吴伟; 吴圣楣; 敖黎明; 王贵琴;

【Author】 Huang Ping, Wu Wei, Wu Shengmei , Ao Liming, Wang Guiqin. Shanghai Children’s Medical Center, Shanghai Second Medical University, Shanghai 200127

【机构】 上海第二医科大学附属上海儿童医学中心; 上海市儿童医院; 上海市普陀区妇婴保健院 200127; 200127; 200127;

【摘要】 为探讨母乳中生长抑素的存在、变化规律及作用,应用放射免疫法系列观测30名正常哺乳产妇乳汁及相对应的血浆中生长抑素水平。结果:母乳生长抑素水平3倍~4倍于母血。母乳中该激素水平自产后7天起持续显著下降(P均<0.05),至产后3月其变化趋于平缓。结果表明,母乳中高浓度的生长抑素极可能有助于维持新生儿消化机能平衡;降低哺乳妇女乳腺癌发病率。

【Abstract】 To study the existence, change and function of somatostatin in human milk, radioimmunoassay was used to detect a series of somatostatin levels in the milk and the corresponding plasma of 30 normal nursing mothers. The somatosta-tion levels in the milk are 3 to 4 times those in the plasma. It begins to lower significantly in succession since 7 days postpar-tum (p all<0. 05) , and then remains stable since 3 months postpartum. The high - level somatostation in human milk may facilitate the homeostasis of neonatal digestive function and reduce the incidents of breast cancer in nursing mothers.

【关键词】 母乳; 喂养; 生长抑素;
【Key words】 breast milk feeding somatostatin;
【基金】 上海市高等学校科学技术发展基金 编号95B13
  • 【文献出处】 临床儿科杂志 ,The Journal of clinical Pediatrics , 编辑部邮箱 ,2000年01期
  • 【分类号】R174
  • 【被引频次】11
  • 【下载频次】63
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