【摘要】 应用放免技术对 5 0例慢性充血性心衰 (CHF)病人血浆甲状腺激素进行了测定。结果表明 :CHF病人三碘甲状腺原氨酸 (T3) ,游离三碘甲状腺原氨酸 (FT3)均显著低于正常组 ,促甲状腺素 (TSH)则升高 ;不同程度心功能CHF患者比较 ,心功能愈差 T3、FT3下降愈明显 ,心功能四级患者伴有甲状腺素 (T4)、游离甲状腺素 (FT4)下降 ;不同心脏疾患 CHF患者比较 ,肺心病心衰患者 T3、FT3下降最为明显。更多还原

【Abstract】 Objective:To study the change and clinical significance in the concentration of thyroxin in blood of patients with chronic congestive heart failure (CHF).Method:Applying radioimmunoassay,50 patients with CHF and 100 normal adults were determined.Results:Levels of serum T 3 and FT 3 in patients with CHF was lower those in healthy controls ( P <0.001)but TSH was raised. Comparison between CHF patients with various degrees of cardiac function showed the worse the cardiac function the more evident reduction of T 3 and FT 3,and paetients with class Ⅳ cardiac function were accompanied by reduction of T 4 and FT 4 .Comparison between CHF patients with different kinds of cardiac diseases, the most prominent reduction of T 3 and FT 3 was found in those with pulmonary heart disease.Conclusion:The level of thyroxin can be used as an indication of cardiac function and has instructive value for the prognosis of heart failure.更多还原