【摘要】 目的　为探讨氧化型低密度脂蛋白 (Ox -LDL)对动脉粥样硬化的致病作用和临床意义。方法　我们利用克隆抗体酶联免疫吸附试验 ,定量测定了 2 0 0例急性心脑血管病患者和 2 0 0例健康对照者血浆中氧化型低密度脂蛋白 (Ox -LDL)的水平。结果　显示急性心脑血管病患者血中Ox -LDL含量 (886 .7± 2 48.9μg/L) ,明显高于对照组 (32 3.1± 83.0 μg/L)。 结论　血中氧化型低密度脂蛋白参与与动脉粥样硬化的发病 ,抗低密度脂蛋白的氧化修饰是预防和治疗心脑血管疾病的重要措施。更多还原

【Abstract】 Objective To approach into the pathogenetic effect of oxidized low density lipoprotein(Ox-LDL) atherosclerosis and its clinical significance. Methods The level of the plasma Ox-LDL in 200 patients with acute atherosclerosis and 200 healthy persons were observed and compared by monocloud antibody ELISA. Results It was shown that plasma Ox-LDL level was 886.7±248.9μg/L in 200 patients with atherosclerosis, significantly higher than that in 200 normal subjects (323.1±83.0μg/L). Conclusion The results suggest that Ox-LDL takes part in the pathogenesis of atherosclerosis and anti-oxidative modification of low density lipoprotein is a measure to prevent and treat cardiocerebrovascular diseases.更多还原