【摘要】 目的 报道马尔尼菲青霉病在中国可继发于艾滋病。方法 详细询问病史，系统查体，进行胸部 X线及肝脾 B超检查及取血、骨髓、皮疹分泌物做病原学检查，真菌培养与鉴定。结果 病人以发热、皮疹、肺炎、贫血、肝脾与淋巴结肿大为主要临床表现。两年前曾感染 HIV。实验室检查：抗 HIV阳性，周围血淋巴细胞总数显著减少， Th2％， Ts54％， Th/Ts比例倒置。骨髓细胞学检查细胞间及部分组织细胞浆内可见大量病原体，真菌培养证实为马尔尼菲青霉菌。结论 在我国，马尔尼菲青霉病可继发于艾滋病，确诊时须排除组织胞浆菌病。更多还原

【Abstract】 Objective To report the penicillinosis marneffei secondary AIDS in China. Methods The diagnosis was made by history of disease, physical examination, roentgenogram of chest, and ultrasonography of liver, spleen. The pathogen was identificated by culturing from the blood, bone marrow and secretion of skin rashes. Results The manifestations of patient included fever, skin rashes, pneumonia, anemia, liver and spleen enlargement and lymphadenectasis. The patient was infected with HIV two years ago. A positive antiboby of HIV was presented, count of lymphocyte was decresed. CD4: was 2％ , CD8:was 54％ ,and CD4/CD8 was smaller than 1.The pathogen was found in cytoplasm and intercellular space by bone marrow smear. The Penicillium marneffei was identificated by fungous culturing. Conclusion We found the penicillinosis marneffei secondary AIDS in China. The key point is exclusion of histoplasmosis.更多还原