节点文献
8-Cl-cAMP对人恶性胶质瘤TJ899细胞c-myc基因表达的影响
Effects of 8-Cl-cAMP on the expression of c-myc gene in human malignant gliomatosis TJ899 cells
【摘要】 目的:观察8-Cl-cAMP对人恶性胶质瘤TJ899XLEQ c-myc基因表达的影响。方法:体外分组培养TJ899细胞,采用原位杂交方法观察实验组和对照组TJ899细胞c-myc基因表达情况。结果:加8-Cl-cAMP的实验组较不加8-Cl-cAMP的对照组TJ899细胞c-myc基因表达降低。结论:8-Cl-cAMP可下调TJ899细胞 c-myc基因表达。
【Abstract】 Objective:To observe the effects of 8-Cl-cAMP on the expression of c-myc gene in human malignant gliomatosis TJ899 cells.Meth- ods:TJ899 cells were cultured in vitro,the expression of c-myc gene wre studied by in situ hybridization.Results:The expression of c-myc gene in the experimential group which added 8-Cl-cAMP was weaker than that in the control group which no 8-Cl-cAMP added. Conclusion:8-Cl-cAMP could suppress the gene expression of c-myc in YJ899 cells.
【关键词】 8-Cl-cAMP TJ899;
原位杂交;
基因表达;
【Key words】 Cl-cAMP TJ899 cell line In situ hybridization Gene expression;
【Key words】 Cl-cAMP TJ899 cell line In situ hybridization Gene expression;
- 【文献出处】 河南实用神经疾病杂志 ,Henan Journal of Practical Nervons Diseases , 编辑部邮箱 ,2000年05期
- 【下载频次】10