【摘要】 目的　通过对慢性粒细胞白血病 (CML )预后的检测 ,指导 CML治疗方案的选择。方法　应用 Cox模型对 5 9例 CML患者进行回顾性分析。结果　高危组 32例 ,中危组 2 7例 ,无一例低危组 ,高、中危组 2年急变率分别为 2 8%和 7% ,3年急变率分别为 5 3%和 14%。结论　在影响预后的许多因素中 ,脾脏大小及末梢中原始细胞的百分数是最危险的因素 ,红细胞压积对 46岁以下患者的预后亦有意义 ,而血小板计数对判断 CML 预后在高、中危组中差异并不显著。更多还原

【Abstract】 Objective:To guide the selection for treatment to chronic myelogenous leukemia(CML),with the inspection of CMLs Prognosis.Method:Fifty nine patients with CML were analysed retrospectively by using the Cox medel.Results:There were 32 cases in the higher risk group and 27 cases in the intermediate group,and none in the lower risk group.The 2 year blastic rates for the two groups were 28% and 7%,The 3 year blastic rates were 53% and 14%.Conclusions:Spleen size and in percent of circulating blasts were the most important among the several risky factors which had prognostic significance.Hematorit became more significant in the younger population who aged less than 46 years.There were not any significant differences platelet count between the higher risk and intermediate groups.更多还原