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雷公藤多甙诱导HL-60细胞凋亡
Apoptosis induced by tripterygium glycosides in HL-60 cells
【摘要】 目的:探讨雷公藤多甙对 HL 60细胞凋亡的作用。方法:应用细胞形态学检查, DNA凝胶电泳及流式细胞仪分析检测。结果: HL 60细胞加上雷公藤多甙 10mg/L孵育 72h,流式细胞仪检测细胞凋亡率为 29.4%(与空白对照组比较, P
【Abstract】 Objective: The current study was designed to investigate the effect of apoptosis of HL 60 cells induced by tripterygium glycosides. Methods: Following treatment with tripterygium glycosides,cell apoptosis was determined by checking the morphology of the cells, agarose gel electrophoresis of DNA fragmentation and quantitation of apoptotic cells by using of flow cytometric analysis. Results: Following incubation of the cells with 10 mg/L tripterygium glycosides for 72 hours,the percentage of apoptotic cells was 29.4%( compared with control,P
- 【文献出处】 癌症 ,Chinese Journal of Cancer , 编辑部邮箱 ,2000年12期
- 【被引频次】19
- 【下载频次】69