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针刺对实验性脊髓损伤前角运动神经元酶学的影响

Effect of Acupuncture on Enzymology of Motor Neuron of Anterior Horn of Experimental Spinal Cord Injury in Rats

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【作者】 吴永刚; 刘成德; 陈潜; 房丽; 孙申田;

【Author】 Wu Yonggang, Liu Chengde, Chen Qian, et al. The Second Affiliated Hospital of Heilongjiang University of TCM, Harbin (150001)

【机构】 黑龙江中医药大学附属第二医院!哈尔滨150001; 哈尔滨医科大学第一临床医学院;

【摘要】 目的:探讨针刺对大鼠脊髓损伤前角运动神经元酶学的影响。方法:采用酶组织化学染色方法定性分析针刺治疗前后脊髓前角运动神经元乙酰胆碱酯酶(ACHE)、琥珀酸脱氢酶(SDH)、酸性磷酸酶(ACP)的含量变化;同时,运用全自动图像分析仪系统进行定量分析。结果:脊髓损伤后ACHE和SDH含量减少(P<001);ACP含量增加(P<001)。而针刺组针刺后均较对照组同时段点ACHE、SDH酶含量高;ACP酶含量低(P<005,P<001)。结论:针刺能调节脊髓损伤后前角运动神经元酶含量,具有抑制或延缓神经元变性程度并能促进其恢复。

【Abstract】 Objective: To study the effect of acupuncture on enzymology of the motor neuron of anterior horn of injured spinal cord in rats. Methods: Chemical staining method was used to quantitively analyze the acetylcholinesterase (ACHE), succinate dehydrogenase (SDH), acid phosphatase (ACP), changes in motor neuron of anterior horn of spinal cord simultaneously, and auto analysis photogram apparatus was used to quantitatively analyze. Results: After spinal cord was injured, the AchE and SDH reduced, ACP raised; in the acupuncture group, ACHE and SDH were increased and ACP was lowered after acupuncture (P<0 05,P<0 01). Conclusion: Acupuncture could regulate enzymology of the motor neuron of anterior horn of injured spinal cord. Acupuncture cuold inhibit or delay the deterioration of neuron, and also could promote the recovery.

【基金】 国家自然科学基金!No .39570 883
  • 【文献出处】 中国中西医结合杂志 ,Chinese Journal of Integrated Traditional and Western Medicine , 编辑部邮箱 ,1999年12期
  • 【分类号】R245
  • 【被引频次】51
  • 【下载频次】169
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