【摘要】 本文用水迷宫实验及测定脂质过氧化物的方法研究了轮叶党参水提取液对实验动物益智作用及抗氧化作用。结果表明,4g/kg和8g/kg轮叶党参水提取液均明显缩短老年小鼠在水迷宫试验中潜伏期并明显减少水迷宫试验的错误次数。说明给予轮叶党参组小鼠学习记忆速度较老年对照组快。轮叶党参水提取物明显降低小鼠脑组织和红细胞及大鼠红细胞中脂质过氧化物(LPO)含量,且明显提高成年大鼠血清中的SOD活性。提示轮叶党参水提取液有改善老年小鼠学习记忆的作用,并能清除老年小鼠体内的脂质过氧化产物。更多还原

【Abstract】 The water labyrinth test and determining lipid peroxid (LPO) contents were used to assay the effects of Codonop-sis lanceolata on promoting intelligence development and lipid peroxide. The results showed that latent period of old mice in water labyrinth was statistically shorten and the number of mistake of old mice was visibly reduced by drinking extraction of Codonopsis lanceolate 4g/kg and 8g/kg. These indicated that mice drinking extraction of Codonopsis lanceloata learned faster that those of drinking water. The contents of IPO in red blood cell and brain of mice and rate drinking extraction of Codonopsis lanceolata were significantly reduced, the activities of superoxide dismutase (SOD) in serum of rat drinking extraction of Codonopsis lanceolata were visibly increased. These presents that the extraction of Codonopsis lanceolata has the role of promoting learning and memory of old animal, its mechanism might be increasing SOD activity and decreasing LPO level.更多还原