【摘要】 为了探讨急、慢性丙型肝炎病人血清抗E2抗体的临床意义．用哺乳动物细胞表达的E2抗原，通过Westernblot检测丙型肝炎病人血清中抗E2抗体。结果37份急慢性丙型肝炎病人血清抗E2抗体在HCVRNA阳性者中检测为59.5％，其中急性患者中检出率为30％，慢性患者中检出率为70．3％。提示抗E2抗体可以作为检测HCV感染有价值诊断指标之一。更多还原

【Abstract】 Antibody response against E2 glycoprotein in hepatitis C virus was studied in 37 patients with acute orchronic hepatitis C. E2 glycoprotein expressed in mammalian cells was used to detect specific antibody (anti-E2)in samples obtained by Western blot from patients with acute and chronic hepatitis C.These results showed thatanti-E2 could be detected in 59.5% of the patients including 3 of 10 acute patients and 19 of 27 chronic patients.It is suggested thatanti-E2 is an useful marker for determining HCV.更多还原