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细菌L型的医院感染及其质粒谱分析研究

Study on the L form Bacteria Nosocomial Infection with Plasmid Profile Analysis

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【作者】 陈端单斌陈德昌张秋霞骈淮燕谢琼

【Author】 Chen Duan Shan Bin Chen Dechang Zhang Qiuxia Pian Huaiyan Department of Clinical Laboratory, First Hospital, Kunming Medical college, Kunming 650032

【机构】 昆明医学院第一附属医院

【摘要】 目的为了全面防止医院感染,我们对细菌L型的医院感染进行了研究。方法对医院内环境中800份标本及医院感染患者918份标本分离出的金黄色葡萄球菌L型、大肠埃希氏菌L型及铜绿假单胞菌L型进行了质粒谱分析和药敏试验。结果本院环境及医院感染患者细菌L型总检出率分别为19.0%和16.7%。不同来源的3种细菌L型的多重耐药性无显著性差异。不同来源3种细菌L型的同源性比例均较高,分别为90.3%、75.0%、84.2%。结论细菌L型医院感染患者的病原菌主要来自医院内环境

【Abstract】 OBJECTIVE In order to prevent nosocomial infection, the L form bacteria were studied. METHODS 800 samples carried out from the hospital envionment and 918 samples from the nosocomial infected patients. Three strains of L forms (Staphyoeocaus aureus L form, Eschherichia colo L from, Pandomonos L form). were isolated and identified. RESULTS The general culture positive rates of 3 strains of L form bacteria of the hospital environment and the nosocomial patients were 19.0% and 16.7% respectiveoy. The multiple antbiotic resistance tests of the three strains from two different origins were of no significante difference (P>0.01). The homology ratios of the three strains of L form bacteria from two different origins were ruther high ie, 90.3%, 75.0% and 84.2% respectively. CONCLUSIONS The pathogenic organisms of the nosocomial infected patients by L form bacteria may be contamincded from the hospital environment.

【基金】 云南省科委应用基础研究资金资助
  • 【文献出处】 中华医院感染学杂志 ,CHINESE JOURNAL OF NOSOCONMIOLOGY , 编辑部邮箱 ,1999年03期
  • 【分类号】R378
  • 【被引频次】1
  • 【下载频次】37
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