【摘要】 目的评价准分子激光屈光性角膜切削术（ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅｋｅｒａｔｅｃｔｏｍｙ，ＰＲＫ）术后因屈光回退、欠矫出现的残留近视及严重角膜上皮下雾状混浊（ｈａｚｅ）而再次手术治疗的疗效及安全性。方法采用准分子激光仪对－１．００～－１６．５０Ｄ的近视眼及近视散光患者进行治疗。ＰＲＫ术后３５例（５１只眼）患者出现残留近视及严重ｈａｚｅ。结合ＰＲＫ手术及准分子激光治疗性角膜切削术（ｐｈｏｔｏｔｈｅｒａｐｅｕｔｉｃｋｅｒａｔｅｃｔｏｍｙ，ＰＴＫ）对以上患者进行再次治疗。结果再次手术后１２个月，全组裸眼视力≥０．５、≥１．０者分别为８２．６％、３９．１％，其中在低、中度近视眼中分别为１００．０％、５０．０％，高度近视眼中分别为７３．３％、３３．３％。全组实际屈光矫正度在预测矫正度±１．００Ｄ者为８６．３％。再次手术后ｈａｚｅ程度比首次手术后轻。结论首次ＰＲＫ术后因屈光回退、欠矫而出现的残留近视及严重ｈａｚｅ可以成功地再治疗，尽管再次治疗的成功率较首次手术低，但再次治疗仍不失为进一步提高ＰＲＫ疗效的有效方法。更多还原

【Abstract】 Objective To evaluate the efficacy and safety of reoperation of residual myopia because of regression, undercorrection with or without coexisting severe corneal haze after excimer laser photorefractive keratectomy (PRK). Methods A VISK 20/20 excimer laser was used to treat myopia of -1.00 to -16.50 diopters (spherical equivalent) at corneal plane. 35 patients (51 eyes) who had residual myopia because of regression, undercorrection with or without coexisting severe corneal haze after initial PRK were retreated by using PRK and phototherapeutic keratectomy. Results At 12 months after retreatment, the rates of uncorrected visual acuity more than or equal to 10/20 or 20/20 were 82.6% and 39.1% respectively, 100.0% and 50.0% in myopia up to -6.00 D, 73.3% and 33.3% in myopia of -6.25 to -16.50 D respectively. 86.3% of eyes were within 1.00 diopters of desired emmetropia. Corneal haze after retreatment was not greater than that observed after initial procedures. Conclusions The residual myopia because of regression, undercorrection with or without severe corneal haze after initial PRK can be successfully retreated. Although the therapeutic result of retreatment of PRK is less successful than that of the initial procedure, retreatment appears to enhance it.更多还原