【摘要】 目的　探讨阻塞性睡眠呼吸暂停综合征 (obstructivesleepapneasyndrome ,OSAS)患者戴用口腔矫治器后 ,其上气道磁共振 (magneticresonanceimaging ,MRI)影像发生的改变。方法　选择 11例有治疗前后多导睡眠图评价、磁共振影像资料完整的OSAS患者 ,用于研究矫治器对上气道的形态学改变 ;另选 11名性别、年龄配比的无睡眠呼吸障碍者 ,作为MRI三维形态研究的对照组。结果　经口腔矫治器治疗后 ,OSAS上气道的内径、截面积、体积均有增大 ,总体积由 ( 12 2 7± 4 13 )ml增加到( 13 93± 4 5 8)ml(P <0 0 1) ;口咽由 ( 5 5 5± 2 10 )ml增加到 ( 6 88± 2 2 6)ml(P <0 0 0 1)。但治疗后的OSAS患者与无睡眠呼吸障碍者比较 ,仍存在鼻咽较小、软腭及舌体较大的差异。结论　口腔矫治器可明显扩张上气道 ,以口咽部为主 ;治疗后的OSAS上气道仍与正常对照存在差异。MRI作为一种影像学手段 ,在OSAS研究中有独到和重要的作用。更多还原

【Abstract】 Objective To investigate the upper airway changes after wearing dental appliance in obstructive sleep apnea syndrome(OSAS) Methods The research included 11 aged OSAS patients and 11 matched controls Through dental appliance therapy the OSAS was proved by polysomnography to have ideal treatment results (AHI had decreased from 44 6±22 5 per hour to 7 53±6 44 per hour) Magnetic resonance imaging (MRI) had been performed before and after wearing dental appliance The MRI images of upper airway after wearing dental appliance were compared with those of without wearing, and even with those of the controls Results After wearing dental appliance the size of upper airway increased greatly, from 12 27 ml±4 13 ml to 13 93 ml±4 58 ml( P <0 01),While the size of oropharynx was increased from 5 55 ml±2 10 ml to 6 88 ml±2 26 ml( P <0 001) There was still remained significant difference at nasopharynx, soft palate and tongue compared with the matched controls Conclusion Dental appliance worked with the effect of enlarging upper airway The abnormal airway morphology can not be changed completely by dental appliance treatment MRI technique, especially the 3 D reconstruction model of upper airway,is an effective and special method in OSAS research更多还原