【摘要】 目的　探讨上腔静脉切除行人工血管置换在晚期肺癌外科治疗中的作用、技术方法及其预后。方法　全组共２６ 例，右侧中心型肺癌２１ 例、周围型肺癌５ 例。行肺癌原发病变、转移淋巴结及受侵及的上腔静脉切除，采用人工血管置换切除的上腔静脉。术后口服小剂量抗凝剂短期治疗，并进行长期的随访与观察。结果　全组无术中及术后早期死亡，无术后近期及远期上腔静脉及无名静脉梗阻症状的发生。随访２３ 例，１、３、５ 年生存率分别为８５％ （２２／２６） 、３９％ （７／１８） 、３６％ （４／１１） 。结论　人工血管置换受侵及的上腔静脉使部分晚期肺癌获得根治性切除，扩大了肺癌外科手术适应证，提高了晚期肺癌患者的生存率，可在晚期肺癌的外科治疗中推荐应用。更多还原

【Abstract】 Objective To investigate the effect, surgical technique and prognosis of replacement of the superior vena cava(SVC) with vascular prosthesis in surgical treatment of advanced lung carcinoma Methods Twenty six patients with right lung carcinoma invading the SVC (central lung carcinoma in 21 cases, peripheral lung carcinoma in 5 cases) underwent radical resection of tumor with concomitant replacement of SVC with vascular prosthesis All patients took a low dose of anticoagulant in short term after operation Long term follow up was conducted Results All the cases had no intraoperative or postoperative early death, and no early or late obstruction of SVC Follow up was conducted in 23 cases The overall survival rates at 1,3 and 5 years were 85%(22/26), 39%(7/18) and 36%(4/11) respectively Conclusions Combination of resection of tumor and replacement of SVC enabled some cases of advanced lung carcinoma to achieve complete resection This surgical technique extended the indications of surgical treatment of lung carcinoma, and increased the survival rate of advanced lung carcinoma Further clinical applications are recommended更多还原