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1020例免疫性不孕患者的治疗结果分析

Analysis on the Treatment of 1 020 Patients with Immunologic Infertility

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【作者】 王丽黄萍黄晓燕万启智

【Author】 WANG Li, HUANG Ping, HUANG Xiaoyan, et al. Chengdu Technology Institution of Fertility Regulation, Chengdu 610031

【机构】 成都市计划生育技术指导所

【摘要】 目的探讨女性免疫性不孕患者的综合治疗效果。方法对原发及继发不孕的妇女血清进行抗精子抗体(ASAb)、抗卵巢抗体(AOAb)、抗内膜抗体(EMAb)、抗绒毛膜促性腺激素抗体(hCGAb)的检测,发现其阳性率分别为:25.88%、22.86%、32.81%、23.61%。采用地塞米松、维生素E、维生素C进行周期性治疗,3个周期为1疗程。结果1疗程后,4种抗体转阴率均可达90%以上,妊娠率平均达30%。结论皮质激素可以减少或消除免疫性不孕患者血清中抗体对妊娠各环节的影响,从而达到治疗不孕的目的。

【Abstract】 Objective To investigate the treatment for immunologic infertility. Methods Serum antisperm antibody, anti ovarian antibody, anti endometrial antibody and anti hCG antibody in 1 020 female patients with primary or secondary infertility were tested. Patients were treated with dexamethasone, vitamin E and vitamin C for 3 cycles consecutively as one course. Results The detective rates of the above antibodies were 25.88%, 22.86%, 32.81% and 23.61% respectively. After one course of treatment, the disappearance rates of the antibodies mentioned were over 90%, and the average pregnancy rate was up to 30%. Conclusion Corticosterocls may reduce or even eliminate the effects of the immune factors on infertility.

  • 【文献出处】 中华妇产科杂志 ,Chinese Journal of Obstetrics And Gynecology , 编辑部邮箱 ,1999年04期
  • 【被引频次】45
  • 【下载频次】244
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