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羊红膻根中羊红膻素G等的分离和鉴定

Separation and Identification of Thellungianin G from the Root of Pimpinella thellungiana Wolff.

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【作者】 乔博灵; 王长岱; 李富贤; 米彩峰; 石惠丽; 高嵨纯子;

【Author】 Qiao Boling, Wang Changdai, Li Fuxian, Mi Caifeng, Shi Huili (Institute of Chinese Materia Medica,Shaanxi Provincial Academy of Traditional Chinese Medicine and Materia Medica, Xi ,an 710003) Shi Haili(Mitsubishi Chemical Industries,Limited)

【机构】 陕西省中医药研究院中药研究所!西安710003; 日本三菱化成综合研究所;

【摘要】 目的:对羊红膻根进行降压有效成分的分离和鉴定。方法:采用柱层色谱法进行分离,光谱技术鉴定化合物的结构。结果:从其根中分得3个化合物,2(1′,2′环氧基)丙基4甲氧基苯酚(2″甲基)丁酸酯(Ⅰ),4(1丙烯基)苯酚(Ⅱ),2甲基丁酸(Ⅲ)。结论:Ⅰ为一新化合物,定名为羊红膻素G,Ⅱ,Ⅲ为首次从该植物中分离得到。

【Abstract】 Objective:To study the effective components in the root of Pimpinella thellungiana Method:Column chromatography with silica gel and ODS was employed for the isolation and purification of ingredients. Their structures were elucidated by spectral analysis.Result:Three compounds were obtained and identified as 2 (1′,2′ epoxy) 4 methoxy pheryl 2 methyl butyrate(Ⅰ),4 (1′ propenyl) phenol(Ⅱ)and 2 methyl butyric acid(Ⅲ).Conclusion:Compound Ⅰis a new compound and named thellungianin G.Compounds Ⅱ and Ⅲ were separated from P. Thellungiana for the first time.

  • 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,1999年09期
  • 【分类号】R284
  • 【被引频次】2
  • 【下载频次】126
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